Cyclodextrin-grafted cellulose: Physico-chemical characterization

Pharmaceutical composition of valsartan: beta-cyclodextrin: physico-chemical characterization and anti-hypertensive evaluation.

Valsartan, a water-insoluble drug, is mainly used in the treatment of hypertension albeit with reduced oral bioavailability. The aim of work was to develop a valsartan:beta-cyclodextrin (VAL:beta-CD) pharmaceutical composition in order to improve its water solubility and bioavailability. The VAL:beta-CD complexes were prepared by the kneading, solid dispersion and freeze-drying methods, of whic...

Inclusion Complexes of Hesperidin with Hydroxypropyl-β - Cyclodextrin. Physico-chemical Characterization and Biological Assessment

The aim of this research was to prepare the inclusion complexes formed by hesperidin and (2-hydroxypropyl)-β-cyclodextrin by different techniques (kneading, co-evaporation and lyophilization methods), to carry out phase solubility studies, in vitro dissolution, antioxidant and antimicrobial tests. To confirm the inclusion compounds formation, spectroscopic (UV-Vis, FTIR, 1 H-NMR) and thermal (D...

Bacterial Cellulose-polyhydroxyalkanoates Composites Synthesis, physico-chemical characterization and biological evaluation for tissue engineering

CATALIN ZAHARIA1, EUGENIU VASILE1, BIANCA GALATEANU2, MIHAELA-CRISTINA BUNEA1, ANGELA CASARICA3, PAUL OCTAVIAN STANESCU1* 1University Politehnica of Bucharest, Advanced Polymers Materials Group 149 Calea Victoriei, 010072 Bucharest, Romania 2University of Bucharest, Department of Biochemistry and Molecular Biology, 34-36 M. Kogalniceanu Blv., 050107, Bucharest, Romania 3National Institute for C...

Cellulose Functionalysed with Grafted Oligopeptides

Physico-Chemical Properties and Phase Behavior of the Ionic Liquid-β-Cyclodextrin Complexes

The solubility of β-cyclodextrin (β-CD) in ionic liquids (ILs) and the activity coefficients at infinite dilution (γ13(∞)) of more than 20 solutes (alkanes, aromatic hydrocarbons, alcohols) were measured in four chosen ionic liquids, their mixtures with β-CD, and in the β-CD at high temperatures from 338 to 398 K using the inverse gas chromatography. The intermolecular interactions, inclusion c...